Tegumental Phosphodiesterase SmNPP-5 Is a Virulence Factor for Schistosomes
نویسندگان
چکیده
منابع مشابه
Tegumental phosphodiesterase SmNPP-5 is a virulence factor for schistosomes.
The intravascular trematode Schistosoma mansoni is a causative agent of schistosomiasis, a disease that constitutes a major health problem globally. In this study we cloned and characterized the schistosome tegumental phosphodiesterase SmNPP-5 and evaluated its role in parasite virulence. SmNPP-5 is a 52.5-kDa protein whose gene is rapidly turned on in the intravascular parasitic life stages, f...
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15 16 The intravascular trematode Schistosoma mansoni is a causative agent of schistosomiasis, 17 a disease that constitutes a major health problem globally. In this study we clone and 18 characterize the schistosome tegumental phosphodiesterase (SmNPP-5) and evaluate its 19 role in parasite virulence. SmNPP-5 is a 52.5 kDa protein whose gene is rapidly turned 20 on in the intravascular parasit...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2011
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.05431-11